Dr. Ashraf Dallol

Ashraf Dallol - Ph.D


Scientific Profile:

Dr Dallol has over 10 years of post-doctoral experience with emphasis on cancer research utilizing genetic and epigenetic up-to-date technologies and approaches. His enthusiasm for research and hard work has resulted in accumulating over 30 high-quality publications that is cited over 1000 times and with an H-Index of 17. His multidisciplinary approach has put him in a position to oversee the epigenetic profiling of cancer as well as elucidating the molecular mechanisms underlying congenital hearing loss in the Kingdom of Saudi Arabia.

Since his arrival at the CEGMR, he played a pivotal role in establishing the hearing loss program and established very useful collaborations to build up representative cohort of samples. This work has resulted in a publication in an international journal and research grants of two research proposals totaling an approximately 4,500,000 SAR. His current research utilizes next-generation sequencing technology to perform whole-genome sequencing, whole-exome sequencing and genome-wide methylation analysis. Dr Dallol has co-founded a new 50,000,000 SAR research center at King Abdulaziz University to utilize the power of high-throughput sequencing in the delivery of Personalized Medicine to the people of Jeddah.


Funded Projects:

1. Towards Establishing a Roadmap for the Breast Cancer Epigenome in Saudi Arabia (ARP-29-292). KACST. Principal Investigator.

2. Personalized Medicine: Application of High Throughput Sequencing Technologies. Strategic Research Funds. Co-Investigator KACST Strategic 09-BIO818-03.

3. High-Throughput Sequencing of Hearing Loss cases in Saudi Arabia. KACST. Co-investigator.

4. Joint Applicant, Technology Innovation Center in Personalized Medicine. KACST.

 

Recent Publications:

• Buhmeida A, Merdad A, El-Maghrabi J, Hidmi J, Boghas A, Al-Qahtani M, Dallol A. (2011) RASSF1A methylation is Predictive of Poor Prognosis in breast cancer in the background of overall low methylation frequency. Anticancer Research. 31(9):2975-81. [IF=1.656] (Corresponding Author).

• Al-Qahtani, M.H., Baghlab, I., Chaudhary, A.G., Abuzenadah, A.M., Bamanie, A., Daghistani, K. J., Safieh, M., Fida, L., Dallol, A.(2010) Spectrum of GJB2 mutations in a cohort of Nonsyndromic Hearing Loss Cases from the Kingdom of Saudi Arabia. Genet Test Mol Biomarkers, 14(1):79-83. [IF=0.879] (Corresponding Author.

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