الانتقال الى المحتوى الأساسي

مركز الابتكار في الطب الشخصي

الأبحاث العلمية

1: Turki RF, Assidi M, Banni HA, Zahed HA, Karim S, Schulten HJ, Abu-Elmagd M,Rouzi AA,Bajouh O, Jamal HS, Al-Qahtani MH, Abuzenadah AM. Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelia polymorphisms and/or consanguinity in Saudi Arabia. BMC Med Genet. 2016 Oct=10;17(Suppl 1):69. PubMed PMID: 27766963; PubMed Central PMCID: PMC5073987.

2: Bibi F, Naseer MI, Alvi SA, Yasir M, Jiman-Fatani AA, Sawan A, Abuzenadah AM, Al-Qahtani MH, Azhar EI. microRNA analysis of gastric cancer patients from Saudi Arabian population. BMC Genomics. 2016 Oct 17;17(Suppl 9):751. PubMed PMID: 27766962; PubMed Central PMCID: PMC5073958.

3: Sheikh IA, Ahmad E, Jamal MS, Rehan M, Assidi M, Tayubi IA, AlBasri SF, BajouhOS, Turki RF, Abuzenadah AM, Damanhouri GA, Beg MA, Al-Qahtani M. Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update. BMC Genomics. 2016 Oct 17;17(Suppl 9):759. Review. PubMed PMID: 27766960; PubMed Central PMCID: PMC5073925.

4: Gari MA, AlKaff M, Alsehli HS, Dallol A, Gari A, Abu-Elmagd M, Kadam R,Abuzinadah MF, Gari M, Abuzenadah AM, Gauthaman K, Alkhatabi H, Abbas MM. Identification of novel genetic variations affecting osteoarthritis patients. BMC Med Genet. 2016 Oct 10;17(Suppl 1):68. Review. PubMed PMID: 27766954; PubMed Central PMCID: PMC5073985.

5: Abu-Elmagd M, Assidi M, Dallol A, Buhmeida A, Pushparaj PN, Kalamegam G, Al-Hamzi E, Shay JW, Scherer SW, Agarwal A, Budowle B, Gari M, Chaudhary A, Abuzenadah A, Al-Qahtani M. The Third International Genomic Medicine Conference (3rd IGMC, 2015): overall activities and outcome highlights. BMC Genomics. 2016 Oct 17;17(Suppl 9):747. PubMed PMID: 27766952; PubMed Central PMCID: PMC5073859.

6: Karim S, Al-Maghrabi JA, Farsi HM, Al-Sayyad AJ, Schulten HJ, Buhmeida A, Mirza Z, Al-Boogmi AA, Ashgan FT, Shabaad MM, NourEldin HF, Al-Ghamdi KB, Abuzenadah A, Chaudhary AG, Al-Qahtani MH. Cyclin D1 as a therapeutic target of renal cell carcinoma- a combined transcriptomics, tissue microarray and molecular docking study from the Kingdom of Saudi Arabia. BMC Cancer. 2016 Sep 30;16(Suppl 2):741. PubMed PMID: 27766950; PubMed Central PMCID: PMC5073805.

7: Dallol A, Daghistani K, Elaimi A, Al-Wazani WA, Bamanie A, Safiah M, Sagaty S, Taha L, Zahed R, Bajouh O, Chaudhary AG, Gari MA, Turki R, Al-Qahtani MH, Abuzenadah AM. Utilization of amplicon-based targeted sequencing panel for the massively parallel sequencing of sporadic hearing impairment patients from Saudi Arabia. BMC Med Genet. 2016 Oct 10;17(Suppl 1):67. Review. PubMed PMID: 27766948; PubMed Central PMCID: PMC5073994.

8: Sheikh IA, Yasir M, Abu-Elmagd M, Dar TA, Abuzenadah AM, Damanhouri GA,Al-Qahtani M, Beg MA. Human sex hormone-binding globulin as a potential target of  alternate plasticizers: an in silico study. BMC Struct Biol. 2016 Sep 30;16(Suppl1):15. PubMed PMID: 27719672; PubMed Central PMCID: PMC5056528.

9: Shaikh S, Rizvi SM, Suhail T, Shakil S, Abuzenadah AM, Anis R, Naaz D, DallolA, Haneef M, Ahmad A, Choudhary L. Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A NeuroinformaticsStudy. CNS Neurol Disord Drug Targets. 2016;15(10):1216-1221. PubMed PMID:27697060.

10: Al-Attas A, Assidi M, Al-Maghrabi J, Dallol A, Schulten HJ, Abu-Elmagd M,Chaudhary A, Abuzenadah A, Budowle B, Buhmeida A, Al-Qahtani M. Enhancement of  Pathologist's Routine Practice: Reuse of DNA Extracted from Immunostained Formalin-fixed Paraffin-embedded (FFPE) Slides in Downstream Molecular Analysis of Cancer. Cancer Genomics Proteomics. 2016 09-10;13(5):399-406. PubMed PMID:27566658.

11: Nedjadi T, Al-Maghrabi J, Assidi M, Dallol A, Al-Kattabi H, Chaudhary A, Al-Sayyad A, Al-Ammari A, Abuzenadah A, Buhmeida A, Al-Qahtani M. Prognostic value of HER2 status in bladder transitional cell carcinoma revealed by both IHC and BDISH techniques. BMC Cancer. 2016 Aug 19;16:653. doi:10.1186/s12885-016-2703-5. PubMed PMID: 27539085; PubMed Central PMCID: PMC4990978.

12: Hussein IR, Magbooli A, Huwait E, Chaudhary A, Bader R, Gari M, Ashgan F,Alquaiti M, Abuzenadah A, AlQahtani M. Genome wide array-CGH and qPCR analysis

for the identification of genome defects in Williams' syndrome patients in Saudi Arabia. Mol Cytogenet. 2016 Aug 12;9:65. doi: 10.1186/s13039-016-0266-4. PubMe PMID: 27525043; PubMed Central PMCID: PMC4981984.

13: Khan F, Ahmed F, Pushparaj PN, Abuzenadah A, Kumosani T, Barbour E, AlQahtani M, Gauthaman K. Ajwa Date (Phoenix dactylifera L.) Extract Inhibits Human Breas Adenocarcinoma (MCF7) Cells In Vitro by Inducing Apoptosis and Cell Cycle Arrest. PLoS One. 2016 Jul 21;11(7):e0158963. doi: 10.1371/journal.pone.0158963. PubMed PMID: 27441372; PubMed Central PMCID: PMC4956039.

14: Kalamegam G, Abbas M, Gari M, Alsehli H, Kadam R, Alkaff M, Chaudhary A, Al-Qahtani M, Abuzenadah A, Kafienah W, Mobasheri A. Pelleted Bone Marrow Derived Mesenchymal Stem Cells Are Better Protected from the Deleterious Effects of Arthroscopic Heat Shock. Front Physiol. 2016 May 24;7:180. doi: 10.3389/fphys.2016.00180. PubMed PMID: 27252654; PubMed Central PMCID: PMC4877393.

15: Karim S, Merdad A, Schulten HJ, Jayapal M, Dallol A, Buhmeida A, Al-Thubaity F, Mirza Z, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH. Low expression of leptin and its association with breast cancer: A transcriptomic study. Oncol Rep. 2016 Jul;36(1):43-8. doi: 10.3892/or.2016.4806. PubMed PMID: 27177292 PubMed Central PMCID: PMC4899016.

16: Dallol A, Buhmeida A, Al-Ahwal MS, Al-Maghrabi J, Bajouh O, Al-Khayyat S, Alam R, Abusanad A, Turki R, Elaimi A, Alhadrami HA, Abuzenadah M, Banni H, Al-Qahtani MH, Abuzenadah AM. Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples. J Transl Med. 2016 May 4;14(1):118. doi: 10.1186/s12967-016-0878-9. PubMed PMID: 27146902; PubMed Central PMCID: PMC4857423.

17: Sheikh IA, Turki RF, Abuzenadah AM, Damanhouri GA, Beg MA. Endocrine Disruption: Computational Perspectives on Human Sex Hormone-Binding Globulin and Phthalate Plasticizers. PLoS One. 2016 Mar 10;11(3):e0151444. doi: 10.1371/journal.pone.0151444. PubMed PMID: 26963243; PubMed Central PMCID PMC4786149.

18: Karim S, Mirza Z, Chaudhary AG, Abuzenadah AM, Gari M, Al-Qahtani MH. Assessment of Radiation Induced Therapeutic Effect and Cytotoxicity in Cancer Patients Based on Transcriptomic Profiling. Int J Mol Sci. 2016 Feb 19;17(2):250. doi: 10.3390/ijms17020250. PubMed PMID: 26907258; PubMed Central PMCID: PMC4783980.

19: Alwazani WA, Zahid R, Elaimi A, Bajouh O, Hindawi S, Arab B, Damanhouri G, Saka MY, Turki R, Khan JA, Dallol A, Abuzenadah AM. Detection of β-Thalassemia Mutations Using TaqMan Single Nucleotide Polymorphism Genotyping Assays. Genet Test Mol Biomarkers. 2016 Mar;20(3):154-7. doi: 10.1089/gtmb.2015.0222. PubMed PMID: 26890443.

20: Rizvi SM, Shaikh S, Naaz D, Shakil S, Ahmad A, Haneef M, Abuzenadah AM. Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease-Diabetes Dual Therapy. Neurochem Res. 2016 Jun;41(6):1475-82. doi: 10.1007/s11064-016-1859-3. PubMed PMID: 26886763.

21: Al-Maghrabi J, Emam E, Gomaa W, Al-Qaydy D, Al-Maghrabi B, Buhmeida A, Abuzenadah A, Al-Qahtani M, Al-Ahwal M. Overexpression of PAK-1 is an independent predictor of disease recurrence in colorectal carcinoma. Int J Clin Exp Pathol. 2015 Dec 1;8(12):15895-902. PubMed PMID: 26884861; PubMed Central PMCID:PMC4730074.

22: Bakhashab S, Ahmed FW, Schulten HJ, Bashir A, Karim S, Al-Malki AL, Gari MA, Abuzenadah AM, Chaudhary AG, Alqahtani MH, Lary S, Ahmed F, Weaver JU. Metformin improves the angiogenic potential of human CD34 ⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction. Cardiovasc Diabetol. 2016 Feb 9;15:27. doi: 10.1186/s12933-016-0344-2. PubMed PMID: 26861446; PubMed Central PMCID: PMC4748498.

23: Salem N, Kamal I, Al-Maghrabi J, Abuzenadah A, Peer-Zada AA, Qari Y, Al-Ahwal M, Al-Qahtani M, Buhmeida A. High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma. Future Oncol. 2016 Feb;12(3):323-31. doi: 10.2217/fon.15.325. PubMed PMID: 26814712.

24: Shaikh S, Shakil S, Abuzenadah AM, Rizvi SM, Roberts PM, Mushtaq G, Kamal MA. Nanobiotechnological Approaches Against Multidrug Resistant Bacterial Pathogens: An Update. Curr Drug Metab. 2015;16(5):362-70. Review. PubMed PMID: 26419545.

25: Rehan M, Ahmad E, Sheikh IA, Abuzenadah AM, Damanhouri GA, Bajouh OS, AlBasri SF, Assiri MM, Beg MA. Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA), 4-Methyl-2,4-bis-(P-Hydroxyphenyl)Pent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight. PLoS One. 2015 Sep 17;10(9):e0138438. doi: 10.1371/journal.pone.0138438. PubMed PMID: 26379041; PubMed Central PMCID: PMC4574962.

26: Agarwal A, Ayaz A, Samanta L, Sharma R, Assidi M, Abuzenadah AM, Sabanegh E. Comparative proteomic network signatures in seminal plasma of infertile men as a function of reactive oxygen species. Clin Proteomics. 2015 Aug 28;12(1):23. doi: 10.1186/s12014-015-9094-5. PubMed PMID: 26321892; PubMed Central PMCID: PMC4552280.

27: Shaikh S, Aaqil H, Rizvi SM, Shakil S, Abuzenadah AM, Gupta P, Saxena S, Tiwari RK, Kumar A. Comparative Inhibition Study of Compounds Identified in the Methanolic Extract of Apamarga Kshara Against Trichomonas vaginalis Carbamate Kinase (TvCK): An Enzoinformatics Approach. Interdiscip Sci. 2016 Dec;8(4):357-365. PubMed PMID: 26310620.

28: Dallol A, Buhmeida A, Merdad A, Al-Maghrabi J, Gari MA, Abu-Elmagd MM, Elaimi A, Assidi M, Chaudhary AG, Abuzenadah AM, Nedjadi T, Ermiah E, Alkhayyat SS Al-Qahtani MH. Frequent methylation of the KLOTHO gene and overexpression of the FGFR4 receptor in invasive ductal carcinoma of the breast. Tumour Biol. 2015 Dec;36(12):9677-83. doi: 10.1007/s13277-015-3733-3. PubMed PMID: 26152288.

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آخر تحديث 9/4/2018 12:35:23 PM