PGD Team Work

Dr. Aisha Elaimi PGD Lab Supervisor
Ms. Asmaa Alaidaroos Lab Specialist	Ms. Sawsan Abuzinadah Lab Technician
Ms. Rukhaa Chaudhary Lab Specialist	Ms. Bayan Aslani Lab Specialist
Mr. Mohammed Aloufi Lab Specialist

Pre-implantation Genetic Diagnosis (PGD)

Pre-implantation genetic diagnosis (PGD) is a procedure used prior to implantation to help identify genetic defects within embryos created through In Vitro Fertilization to prevent certain diseases or disorders from being passed on to the child.

In Vitro Fertilization (IVF)

In Vitro Fertilization includes egg retrieval and fertilization in the lab. The developing embryos on the third day (10-8 cell stage) are genetically screened. Then healthy embryos are transferred to the mother.

Comprehensive Test of Chromosomes (PGD/PGS )

Preimplantation genetic screening PGS can benefit any couple at risk for passing on chromosomal abnormalities.

Who are the recommended cases for PGD/PGS/IVF?

• Sickle cell anemia, Thalassemia and single- gene disorders with confirmed pathogenic mutation.
• If the affected gene is known, a custom PGD protocol will be designed and implemented.
• If the affected gene is unknown to the couple, whole-exome sequencing will be orered to them to maximize the chances of identifying the underlying mutation.
• Recurrent Abortions/Miscarriages (Normal karyotype).
• Recurrent IVF failure (3/2 or more).
• Advance Maternal Age (>38/35).

(PGD-IVF) Steps