ممدوح قاري - دكتوراة


Scientific Profile:

Professor of Hematology and Molecular Genetics, Faculty of Applied Medical Science.


 Educational Qualifications:

  • Doctor of Philosophy (Ph. D)
    Molecular Genetics Division of Genomic Medicine Molecular Hematology Unit University of Sheffield, United Kingdom.
    Oct 1996-Oct 2000

  • Master of Sciences (M Sc.) in Pathological Sciences
    Joint course between Sheffield, Hallam University and Sheffield University Sheffield, United Kingdom.
    Sep 1995-Sep 1996

  • B Sc. in Medical Technology
    Faculty of Medicine and Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
    (Ranked the first among all physicians taking the R5 level)
    1986-1989

  • AFSA in Reproductive Endocrinology and Infertility (University of Pierre and Marie Curie Paris 6) AFSA in Medical Gynecology (University of Pierre and Marie Curie Paris 6) Diploma in gynecological Laparoscopy (University of Auvergne) France Jan. 2009 till Sept. 2011

 Honors or Prizes:

The Young Investigator's Prize for Poster Presentation, Glasgow, 1998. British Society for Hematology.
 
Publcations:

1. Hussein IR, Magbooli A, Huwait E, Chaudhary A, Bader R, Gari M, Ashgan F, Alquaiti M, Abuzenadah A, AlQahtani M (2016) Genome wide array-CGH and qPCR analysis for the identification of genome defects in Williams' syndrome patients in Saudi Arabia. Mol Cytogenet. 12;9:65.
2. Kalamegam G, Abbas M, Gari M, Alsehli H, Kadam R, Alkaff M, Chaudhary A, Al-Qahtani M, Abuzenadah A, Kafienah W, Mobasheri A (2016) Pelleted Bone Marrow DerivedMesenchymal Stem Cells Are Better Protected from the Deleterious Effects of Arthroscopic Heat Shock. Front Physiol. 24;7:180.
3. Karim S, Merdad A, Schulten HJ, Jayapal M, Dallol A, Buhmeida A, Al-Thubaity F, Mirza Z, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH (2016) Low expression of leptin and its association with breast cancer: A transcriptomic study. Oncol Rep. 36(1):43-8.
4. Karim S, Mirza Z, Chaudhary AG, Abuzenadah AM, Gari M, Al-Qahtani MH (2016) Assessment of Radiation Induced Therapeutic Effect and Cytotoxicity in Cancer Patients Based on Transcriptomic Profiling. Int J Mol Sci. 19;17(2):250.
5. Khabaz MN, Nedjadi T, Gari MA, Al-Maghrabi JA, Atta HM, Basuni AA, Elderwi DA (2016) BK polyomavirus association with colorectal cancer development. Genet Mol Res. 6;15(2).
6. Khabaz MN, Nedjadi T, Gari MA, Al-Maghrabi JA, Atta HM, Bakarman M, Gazzaz ZJ (2016) GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population. Genet Mol Res. 29;15(1).
7. Bakhashab S, Ahmed FW, Schulten HJ, Bashir A, Karim S, Al-Malki AL, Gari MA, Abuzenadah AM, Chaudhary AG, Alqahtani MH, Lary S, Ahmed F, Weaver JU (2016) Metformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction. Cardiovasc Diabetol. 9;15:27.
8. Baig M, Gazzaz ZJ, Gari MA, Al-Attallah HG, Al-Jedaani KS, Mesawa AT, Al-Hazmi AA (2015) Prevalence of obesity and hypertension among University students' and their knowledge and attitude towards risk factors of Cardiovascular Disease (CVD) in Jeddah, Saudi Arabia. Pak J Med Sci. 31(4):816-20.
9. Dallol A, Buhmeida A, Merdad A, Al-Maghrabi J, Gari MA, Abu-Elmagd MM, Elaimi A, Assidi M, Chaudhary AG, Abuzenadah AM, Nedjadi T, Ermiah E, Alkhayyat SS, Al-Qahtani MH (2015) Frequent methylation of the KLOTHO gene and overexpression of the FGFR4 receptor in invasive ductal carcinoma of the breast. Tumour Biol. 36(12):9677-83.
10. Ilyas AM, Ahmad S, Faheem M, Naseer MI, Kumosani TA, Al-Qahtani MH, Gari M, Ahmed F (2015) Next generation sequencing of acute myeloid leukemia: influencing prognosis. BMC Genomics. 16 Suppl 1:S5
11. Merdad A, Gari MA, Hussein S, Al-Khayat S, Tashkandi H, Al-Maghrabi J, Al-Thubaiti F,Hussein IR, Koumosani T, Shaer N, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH, Dallol A (2015) Characterization of familial breast cancer in Saudi Arabia. BMC Genomics. 16 Suppl 1: S3.
12. Schulten HJ, Alotibi R, Al-Ahmadi A, Ata M, Karim S, Huwait E, Gari M, Al-Ghamdi K, Al Mashat F, Al-Hamour O, Al-Qahtani MH, Al-Maghrabi J (2015) Effect of BRAF mutational status on expression profiles in conventional papillary thyroid carcinomas. BMC Genomics. 16 Suppl 1: S6.
13. Gari M, Dakhakhni M, Gari A, Alshihri E, Al-Jahdali R, Narasimhan K, Liang S, Al-Sayes F, Kalamegam G, Chaudhary A, Abuzenadah A, Al-Qahtani M (2015) Incidence and potential causative factors associated with chronic benign neutropenia in the Kingdom of Saudi Arabia. BMC Proc. 15;9 Suppl 2:S1.
14. Mirza Z, Schulten HJ, Farsi HM, Al-Maghrabi JA, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH, Karim S (2015) Molecular interaction of a kinase inhibitor midostaurin with anticancer drug targets, S100A8 and EGFR: transcriptional profiling and molecular docking study for kidney cancer therapeutics. PLoS One. 19;10(3).
15. Khabaz MN, Gari MA, Al-Maghrabi JA, Nedjadi T, Bakarman M. (2015) Association between GSTP1 genotypes and hormone receptor phenotype in invasive ductal carcinomas of breast. Asian Pac J Cancer Prev. 16(5):1707-13.
16. Bakhashab S, Lary S, Ahmed F, Schulten HJ, Bashir A, Ahmed FW, Al-Malki AL, Jamal HS, Gari MA, Weaver JU (2014) Reference genes for expression studies in hypoxia and hyperglycemia models in human umbilical vein endothelial cells. G3 (Bethesda). 5;4(11):2159-65.
17. Kari JA, El Desoky SM, Singh AK, Gari MA, Kleta R, Bockenhauer D (2014) The case | Renal tubular acidosis and eye findings. Kidney Int. 86(1):217-8.
18. Mirza Z, Schulten HJ, Farsi HM, Al-Maghrabi JA, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH, Karim S (2014) Impact of S100A8 expression on kidney cancer progression and molecular docking studies for kidney cancer therapeutics. Anticancer Res. 34(4):1873-84.
19. Merdad A, Karim S, Schulten HJ, Dallol A, Buhmeida A, Al-Thubaity F, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH (2014) Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis. Anticancer Res. 34(3):1355-66.
20. Buhmeida A, Dallol A, Merdad A, Al-Maghrabi J, Gari MA, Abu-Elmagd MM, Chaudhary AG, Abuzenadah AM, Nedjadi T, Ermiah E, Al-Thubaity F, Al-Qahtani MH (2014) High fibroblast growth factor 19 (FGF19) expression predicts worse prognosis in invasive ductal carcinoma of breast. Tumour Biol. 35(3):2817-24.
21. Kari JA, Bockenhauer D, Stanescu H, Gari M, Kleta R, Singh AK (2014) Consanguinity in Saudi Arabia: a unique opportunity for pediatric kidney research. Am J Kidney Dis. 63(2):304-10
22. Kari JA, El-Desoky SM, Gari M, Malik K, Vega-Warner V, Lovric S, Bockenhauer D (2013) Steroid resistant nephrotic syndrome: impact of genetic testing. Ann Saudi Med. 33(6):533-8.
23. Schulten HJ, Salama S, Al-Ahmadi A, Al-Mansouri Z, Mirza Z, Al-Ghamdi K, Al-Hamour OA, Huwait E, Gari M, Al-Qahtani MH, Al-Maghrabi J (2013) Comprehensive survey of HRAS, KRAS, and NRAS mutations in proliferative thyroid lesions from an ethnically diverse population. Anticancer Res. 33(11):4779-84.
24. Abuzenadah AM, Zaher GF, Dallol A, Damanhouri GA, Chaudhary AG, Al-Sayes F, Gari MA, AlZahrani M, Hindawi S, Al-Qahtani MH (2013) Identification of a novel SBF2 missense mutation associated with a rare case of thrombocytopenia using whole-exome sequencing. J Thromb Thrombolysis. 36(4):501-6.
25. Ashraf Dallol, Huda Banni, Mamdooh A. Gari, Mohammed H. Al-Qahtani, Adel M. Abuzenadeh, Fatin Al-Sayes, Adeel, G. Chaudhary, Jeffrey Bidwell and Wael Kafienah (2012) Five novel glucose-6-phosphate dehydrogenase deficiency haplotypes correlating with disease severity. Journal of Translational Medicine. in-press.
26. Ashraf Dallol, Jaudah Al-Maghrabi, Abdelbaset Buhmeida, Mamdooh A. Gari, Adeel G. Chaudhary, Hans-Juergen Schulten, Adel M. Abuzenadah, Mahmoud S. Al-Ahwal, Abdulrahman Sibiany, and Mohammed H. Al-Qahtani (2012) Methylation of the Polycomb Group Target Genes (PCGT) is a Possible Biomarker for Favorable Prognosis in Colorectal Cancer, Cancer Epidemiology Biomarkers and Prevention. in-press.
27. Hans-Juergen Schulten, Sherine Salama, Zuhoor Al-Mansouri, Reem Alotibi, Khalid Al-Ghamdi, Osman Abdel Al-Hamour, Hassan Sayadi, Hosam Al-Aradati, Adel Al-Johari, Etimad Huwait, Mamdooh Gari, Mohammed Hussain Al-Qahtani1 and Jaudah Al-Maghrabi (2012) BRAF mutations in thyroid tumors from an ethnically diverse group. Hereditary Cancer in Clinical Practice. 10 (1): 1-7
28. Mamdooh Gari, Fatin Al-Sayes, Farid Ahmed, Abdul Ali Peerzada, Adel Abuzenadah, Lubna S. Mira, Mohammed Al-Qahtani, Ashraf Dallol, Adeel Chaudhary, Mohammed Mahnashi, Ghazi Damanhouri (2012) JAK2 Mutations in Chronic Myeloproliferative Neoplasm; Towards the Application of Personalized Treatments for Saudi Patients, Open Journal of Blood Diseases. 2 (2): 17-21.
29. Shehab Mahmoud Abd El- Kader, Mamdooh A. Gari and Eman Mohamed Salah El-Den Ashmawy (2012) Exercise Training Modulates Insulin Resistance and Inflammatory Cytokines in Obese Non-insulin Dependent Diabetic Patients, Advances in Environmental Biology. 6 (2): 598-604.
30. Al-Sayes1, F, Gari, M, Qusti, S, Bagatian, N and Abuzenadah, A (2011) Prevalence of iron deficiency and iron deficiency anemia among females at university stage, Journal of Medical Laboratory and Diagnosis. 2 (1): 5-11
31. Chaudhary, A.G., Al-Juhani, M.A., Azam, J., Gari, M., Abuzenadah, A., Al-Maghrabi, J. and Al-Qahtani, M. (2011) Evaluation of Her-2/Neu Gene Amplification in Saudi Female Breast Cancer Patients Using Quantitative Real-Time PCR and Fluorescence In situ Hybridisation, World Applied Sciences Journal. 14 (10): 1445-1452.
32. Al-Sayes1, F, Qusti, S, Gari, M, Babaker. (2011) Serum Transferrin Receptor Assay in Iron-Deficiency Anemia and Anemia of Chronic Diseases, Journal King Abdulaziz University Medical Sciences. 18 (3): 3-16.
33. Schulten HJ, Al-Maghrabi J, Al-Ghamdi K, Salama S, Al-Muhayawi S, Chaudhary A, Hamour O, Abuzenadah A, Gari M, Al-Qahtani M. (2011) Mutational screening of RET, HRAS, KRAS, NRAS, BRAF, AKT1, and CTNNB1 in medullary thyroid carcinoma, Anticancer Res. 31 (12): 4179-4183.
34. Mamdooh Gari (2011) Identification of Circulating Endothelial Cells in Peripheral Blood, Research Journal of Medical Sciences. 5 (5): 262-268.
35. Buhmeida A, Merdad A, Al-Maghrabi J, Al-Thobaiti F, Ata M, Bugis A, Syrjänen K, Abuzenadah A, Chaudhary A, Gari M, Al-Qahtani M, Dallol A. (2011) RASSF1A methylation is predictive of poor prognosis in female breast cancer in a background of overall low methylation frequency. Anticancer Res. 31 (9):2975-2981.
36. Abuzenadah AM, Hussein IM, Damanhouri GA, A-Sayes FM, Gari MA, Chaudhary AG, Zaher GF, Al-Attas A, Al-Qahtani MH. (2011) Molecular basis of β-thalassemia in the western province of Saudi Arabia: identification of rare β-thalassemia mutations. Hemoglobin.;35 (4):346-57.
37. Buhmeida A, Al-Maghrabi J, Merdad A, Al-Thubaity F, Chaudhary A, Gari M, Abuzenadah A, Collan Y, Syrjänen K, Al-Qahtani M. (2011) Prognostic value of mitotic counts in breast cancer of Saudi Arabian patients. Anticancer Res. 31 (1):97-103.
38. Al-Khattabi H, Kelany A, Buhmeida A, Al-Maghrabi J, Lari S, Chaudhary A, Gari M, Abuzenadah A, Al-Qahtani M. (2010) Evaluation of HER-2/neu gene amplification by fluorescence in situ hybridization and immunohistochemistry in Saudi female breast cancer. Anticancer Res. 30 (10):4081-4088.
39. Mamdooh Abdullah Gari (2010) Moderate Versus High Intensity Aerobic Exercise Training on Glycemic Control and Anti-Inflammatory Effects on Non-Insulin Dependent Diabetic Patients. World Applied Sciences Journal. 8 (6):667-671.
40. Buhmeida A, Al-Maghrabi J, Merdad A, Al-Thubaity F, Chaudhary A, Gari M, Abuzenadah A, Collan Y, Syrjänen K, Al-Qahtani M. (2010) Nuclear morphometry in prognostication of breast cancer in Saudi Arabian patients: comparison with European and African breast cancer. Anticancer Res. 30 (6):2185-2191.
41. Shehab Mahmoud Abd El-Kader and Mamdooh Abdullah Gari, (2010) Laser Acupuncture Therapy Added to Inspiratory Muscle Training and Postural Drainage Improves Treatment of Children with Bronchopneumonia, Australian Journal of Basic and Applied Sciences, 4 (6): 1001-1006.
42. Shehab Mahmoud Abd El- Kader and Mamdooh Abdullah Gari, (2009) Metabolic Control Response to Weight Reduction in Obese Non-Insulin Dependent Diabetic Patients, World Journal of Medical Sciences. 4 (2): 98-103.
43. Shehab Mahmoud Abd El-Kader and Mamdooh Abdullah Gari, (2009) Physical Training Combined with Dietary Measures and Acupuncture in the Treatment of Adult Obesity. A Comparison of Two Protocols, World Applied Sciences Journal 7 (4): 531-537.
44. Mamdooh Abdullah Gari (2009) Bone Mineral Status Response to Treadmill Walking Exercise in Postmenopausal Women, American-Eurasian Journal of Scientific Research. 4 (4): 246-249.
45. Gari MA, Abuzenadah AM, Chaudhary AG, Al-Qahtani MH, Banni H, Al-Says FM, Lary S and Dmanhouri (2008) Detection of FLT3 oncogene mutations in acute myeloid leukemia using Conformation Sensitive Gel Electrophoresis, International Journal of Molecular Sciences; 9: 2194-2204.
46. Gari MA, Chaudhary AG, Al-Qahtani MH, Abuzenadah AM, Banni H, Al-Sayes FM, Al-Harbi A, and Lary S (2008) Frequency of Mediterranean Mutation among a Group of Saudi G6PD Patients in Western region-Jeddah, International Journal of Laboratory Hematology.
47. Gari MA (2008) Prevalence of iron deficiency anemia among elementary female school children in Northern Jeddah-Saudi Arabia, Journal of King Abdulaziz University-Medical Sciences, 15 (1): 55-65.
48. Adeel G. Chaudhary, Mohammed H. Alqahtani, Adel Abuzenadah, Mamdooh Gari, Abeer A. Al-Sofyani, Jumana Y. Al-Aama, Sahira A. Lary, Aisha H. Elaimi (2008) Mutation analysis in Saudi Duchenne and Becker muscular dystrophy patients using multiplex PCR, Arch Med Sci; 4, (1): 16–21.
49. Gari MA, Abuzenadah AM, Chaudhary AG, Al-Qahtani MH, Al-Says FM and Dmanhouri G (2006) Pilot study of DNA extraction from archival unstained bone marrow slides: comparison of three rapid methods, African Journal of Biotechnology Vol. 5 (6), 532-535.
50. Abu-Duheir FM, Goodeve AC, Wilson GA, Gari M.A., Peake IR, and Reilly JT. (2003) Mutational analysis of class III receptor tyrosine kinase (C-KIT, C-FMS, FLT3) in idiopathic myelofibrosis. British Journal of Haematology, 120, 464-470.
51. Abu-Duheir F.M., Goodeve AC, Wilson G.A., Gari M.A., Peake I.R., & Reilly J. (2002). Mutation analysis of class III receptor tyrosine kinase (RTK III) genes do not play an important role in idiopathic myelofibrosis. The Hematology Journal, 3, 302.
52. Abu-Duheir FM, Goodeve AC, Wilson GA, Gari M.A., Peake IR, and Reilly JT. (2002) Mutational analysis of class III receptor tyrosine kinase (C-KIT, C-FMS, FLT3) in idiopathic myelofibrosis. British Journal of Haematology, 120, 464-470.
53. Abu-Duheir F.M., Goodeve A.C., Wilson G.A., Gari M., Peake I.R., Rees.D.C., Vandenberghe E.A., Winship P.R., and Reilly J.T. (2000) FLT3 internal tandem duplication mutations in adult acute myeloid leukemia define a high-risk group. British Journal of Haematology, page110.
54. Gari M., Goodeve A, Wilson G., Winship P., Langabeer S., Linch D., Vandenberghe E., Peake I. and Reilly J. (1999) c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukemia. British Journal of Haematology, 105:894-900.


للاطلاع على السيرة الذاتية للــ د. ممدوح قاري   اضغط هنا




آخر تحديث
9/4/2018 12:12:22 PM